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Usages de drogues Keflex (Cephalexine)

A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of cephaloridine or cephalothin, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms. Cephalexine (also called Cefalexin) is a first generation cephalosporin antibiotic. It is one of the most widely prescribed antibiotics, often used for the treatment of superficial infections that result as complications of minor wounds or lacerations. It is effective against most gram-positive bacteria.

Comment Prises Keflex (Cephalexine)

The dose of cephalexin for adults is 1 to 4 grams in divided doses. Children are treated with 25-100 mg/kg/day in divided doses.

Mécanisme d'action

Cephalexine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cephalexin interferes with an autolysin inhibitor.

Les effets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; indigestion; joint pain; stomach pain; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; confusion; dark urine; decreased urination; fever; hallucinations; red, swollen, or blistered skin; seizures; severe or blood diarrhea; severe stomach pain; severe tiredness; unusual bruising or bleeding; unusual vaginal pain, odor, or discharge; yellowing of the eyes or skin.

si je manque une dose

Do not miss any doses. If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Stockage

Tablets and capsules should be stored at room temperature. Suspensions should be refrigerated and discarded after 14 days.

Interactions alimentaires

Take on empty stomach: 1 hour before or 2 hours after meals.

Interactions médicamenteuses

Probenecid Probenecid increases the antibiotic's level

Organismes touchés

Enteric bacteria and other eubacteria

Plus informatique sur Keflex (Cephalexine)

Cephalexine may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Cephalexine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Cephalexine may decrease the ability of your blood to clot. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
Be sure to use Cephalexine for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
Cephalexine only works against bacteria; it does not treat viral infections (eg, the common cold).
Long-term or repeated use of Cephalexine may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
Diabetes patients - Cephalexine may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.
Cephalexine may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Cephalexine.
Use Cephalexine with caution in the ELDERLY; they may be more sensitive to its effects.
Use Cephalexine with extreme caution in CHILDREN younger than 10 years old who have diarrhea or an infection of the stomach or bowel.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cephalexine while you are pregnant. Cephalexine is found in breast milk. If you are or will be breast-feeding while you use Cephalexine, check with your doctor. Discuss any possible risks to your baby.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

Synonymes Keflex (Cephalexine)

CEX, Cefalessina (DCIT),Cefalexin,Cefalexin Sodium,Cefalexina (Spanish),Cefalexine (France),Cefalexinum (Latin),Cephalexine 1-hydrate, Cephalexine hydrate,Cephalexine monohydrate,Cephalexinee,Cephalexineum, Alcephin, Cepcid, Cephasun, Cepmax, Phexin Bd, Alexin, Biocef, Carnosporin, Cefadal, Cefadin, Cefalin, Cefax, Ceforal, Cefovit, Cepol, Ceporex, Durantel, Erocetin, Felexin, Fexin, Ibilex, Ibrexin, Kefolan, Lafarine, Larixin, Lenocef, Lopilexin, Madlexin, Mamlexin, Medoxine, Neolexina, Nufex, Oroxin, Palitrex, Sanaxin, Servispor, Sialexin, Tepaxin, Voxxim, Winlex, Zozarine

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