Liste tous les antibiotiques connus

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 * Ilosone
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 * Rifadine
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 * Sumycin
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 * Tetracycline
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 * Zithromax
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Liste des antibiotiques

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Nom du médicament

Zithromax (Azithromycin)

Nom de drogues chimiques

(2R,3S,4R,5R,8R,10R,11R,13S,14R)-11-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

Indication

For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions: H. influenzae, M. catarrhalis, S. pneumoniae, C. pneumoniae, M. pneumoniae, S. pyogenes, S. aureus, S. agal

Usages de drogues Azithromycin

Zithromax is used for treating mild to moderate infections caused by certain bacteria. It may also be used alone or with other medicines to treat or prevent certain infections in persons with advanced HIV infection. It may also be used for other conditions as determined by your doctor.

Comment Prises Azithromycin

Use Zithromax as directed by your doctor. Check the label on the medicine for exact dosing instructions. Take Zithromax by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Zithromax. Zithromax works best if it is taken at the same time each day. To clear up your infection completely, use Zithromax for the full course of treatment. Keep using it even if you feel better in a few days.

Mécanisme d'action

Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells

Absorption

Bioavailability is 37% following oral administration.

Les effets

If you experience any of the following serious side effects, stop taking Zithromax and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue). Other, less serious side effects may be more likely to occur. Continue to take Zithromax and talk to your doctor if you experience nausea, vomiting, diarrhea, or abdominal pain; unusual dizziness, fatigue, or headache; vaginal yeast infection; a rash; or increased sensitivity to sunlight. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

si je manque une dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Stockage

Zithromax tablets should be stored between 15° to 30° C (59° to 86°F). Store constituted suspension between 5° to 30°C (41° to 86°F) and discard when full dosing is completed or within 10 days. Shake well before each use. Oversized bottle provides shake space. Keep tightly closed.

Interaction for Zithromax

Co-administration of nelfinavir at steady-state with a single dose of azithromycin (2 ??600 mg tablets) results in increased azithromycin serum concentrations. Although a dose adjustment of azithromycin is not recommended when administered in combination with nelfinavir, close monitoring for known side effects of azithromycin, such as liver enzyme abnormalities and hearing impairment, is warranted.
Azithromycin did not affect the prothrombin time response to a single dose of warfarin. However, prudent medical practice dictates careful monitoring of prothrombin time in all patients treated with azithromycin and warfarin concomitantly. Concurrent use of macrolides and warfarin in clinical practice has been associated with increased anticoagulant effects.
Drug interaction studies were performed with azithromycin and other drugs likely to be co-administered. When used in therapeutic doses, azithromycin had a modest effect on the pharmacokinetics of atorvastatin, carbamazepine, cetirizine, didanosine, efavirenz, fluconazole, indinavir, midazolam, rifabutin, sildenafil, theophylline (intravenous and oral), triazolam, trimethoprim/sulfamethoxazole or zidovudine. Co-administration with efavirenz or fluconazole had a modest effect on the pharmacokinetics of azithromycin. No dosage adjustment of either drug is recommended when azithromycin is co administered with any of the above agents. Interactions with the drugs listed below have not been reported in clinical trials with azithromycin; however, no specific drug interaction studies have been performed to evaluate potential drug-drug interaction. Nonetheless, they have been observed with macrolide products. Until further data are developed regarding drug interactions when azithromycin and these drugs are used concomitantly, careful monitoring of patients is advised:
Digoxinn~elevated digoxin concentrations.
Ergotamine or dihydroergotaminen~acute ergot toxicity characterized by severe peripheral vasospasm and dysesthesia.
Cyclosporine, hexobarbital and phenytoin concentrations.
Laboratory Test Interactions
There are no reported laboratory test interactions.
Repeat Treatment
Studies evaluating the use of repeated courses of Zmax have not been conducted.

Interactions alimentaires

Do not take Aluminum or magnesium antacids or supplements while on this medication.
Take on empty stomach: 1 hour before or 2 hours after meals.

Organismes touchés

Enteric bacteria and other eubacteria

Plus informatique sur Azithromycin

Avoid prolonged exposure to sunlight. Zithromax may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

Synonymes Azithromycin

Azax, Azilup, Azito, Azizen, Azenil, Azitromax, Aztrin, Hemomycin, Misultina, Mixoterin Setron, Sumamed, Tobil, Tromix, Zeto, Zifin, Zitrim, Zitrotek Aritromicina (Spain),Azithramycine, Azithromycin Dihydrate,Azithromycine(France),Azithromycinum (Latin)

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